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DNA alkylation repair limits spontaneous base substitution mutations in Escherichia coli.

The Escherichia coli Ada and Ogt DNA methyltransferases (MTases) are known to transfer simple alkyl groups from O6-alkylguanine and O4-alkylthymine, directly restoring these alkylated DNA lesions to guanine and thymine. In addition to being exquisitely sensitive to the mutagenic effects of methylati...

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Bibliografske podrobnosti
izdano v:J Bacteriol
Principais autores: Mackay, W J, Han, S, Samson, L D
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1994
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC205492/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8195077/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.11.3224-3230.1994
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