Imbalanced Base Excision Repair Increases Spontaneous Mutation and Alkylation Sensitivity in Escherichia coli

Inappropriate expression of 3-methyladenine (3MeA) DNA glycosylases has been shown to have harmful effects on microbial and mammalian cells. To understand the underlying reasons for this phenomenon, we have determined how DNA glycosylase activity and substrate specificity modulate glycosylase effect...

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Podrobná bibliografie

Vydáno v:	J Bacteriol
Hlavní autoři:	Posnick, Lauren M., Samson, Leona D.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1999
Témata:	Genetics and Molecular Biology
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94142/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10542179/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.181.21.6763-6771.1999
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