Specific Chromosome Alterations in Fluconazole-Resistant Mutants of Candida albicans

The exposure of Candida albicans to fluconazole resulted in the nondisjunction of two specific chromosomes in 17 drug-resistant mutants, each obtained by an independent mutational event. The chromosomal changes occurred at high frequencies and were related to the duration of the drug exposure. The l...

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Bibliografische Detailangaben

Veröffentlicht in:	J Bacteriol
Hauptverfasser:	Perepnikhatka, Valentina, Fischer, Frank J., Niimi, Masakazu, Baker, Rachel A., Cannon, Richard D., Wang, Ying-Kai, Sherman, Fred, Rustchenko, Elena
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Eukaryotic Cells
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC93895/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10383973/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.181.13.4041-4049.1999
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