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Specific Chromosome Alterations in Fluconazole-Resistant Mutants of Candida albicans

The exposure of Candida albicans to fluconazole resulted in the nondisjunction of two specific chromosomes in 17 drug-resistant mutants, each obtained by an independent mutational event. The chromosomal changes occurred at high frequencies and were related to the duration of the drug exposure. The l...

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Detalhes bibliográficos
Main Authors: Perepnikhatka, Valentina, Fischer, Frank J., Niimi, Masakazu, Baker, Rachel A., Cannon, Richard D., Wang, Ying-Kai, Sherman, Fred, Rustchenko, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC93895/
https://ncbi.nlm.nih.gov/pubmed/10383973
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