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Gene Targeting in Penicillium chrysogenum: Disruption of the lys2 Gene Leads to Penicillin Overproduction

Two strategies have been used for targeted integration at the lys2 locus of Penicillium chrysogenum. In the first strategy the disruption of lys2 was obtained by a single crossing over between the endogenous lys2 and a fragment of the same gene located in an integrative plasmid. lys2-disrupted mutan...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Casqueiro, Javier, Gutiérrez, Santiago, Bañuelos, Oscar, Hijarrubia, Maria Jose, Martín, Juan Francisco
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 1999
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC93495/
https://ncbi.nlm.nih.gov/pubmed/9973344
Tagiau: Ychwanegu Tag
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