Lysine α-ketoglutarate reductase as a therapeutic target for saccharopine pathway related diseases
The saccharopine pathway (SacPath) and the pipecolate pathway (PipPath) catabolize lysine to α-aminoadipate. Although the PipPath has been highlighted as the prominent route operating in the brain, recent work has demonstrated that the SacPath plays a major role in lysine catabolism in the brain. Th...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2025-10-01
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| Serija: | Frontiers in Molecular Neuroscience |
| Teme: | |
| Online pristup: | https://www.frontiersin.org/articles/10.3389/fnmol.2025.1695490/full |
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