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Extrahelical cytosine bases in DNA duplexes containing d[GCC](n)·d[GCC](n) repeats: detection by a mechlorethamine crosslinking reaction

The cytosine–cytosine (C–C) pair is one of the least stable DNA mismatch pairs. The bases of the C–C mismatch are only weakly hydrogen bonded, and previous work has shown that, in certain sequence contexts, they can become unstacked from the core helix, and adopt an ‘extrahelical’ location. Here, us...

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Autors principals: Rojsitthisak, Pornchai, Romero, Rebecca M., Haworth, Ian S.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC92524/
https://ncbi.nlm.nih.gov/pubmed/11713322
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