Engineering Increased Stability in the Antimicrobial Peptide Pediocin PA-1

Pediocin PA-1 is a food grade antimicrobial peptide that has been used as a food preservative. Upon storage at 4°C or room temperature, pediocin PA-1 looses activity, and there is a concomitant 16-Da increase in the molecular mass. It is shown that the loss of activity follows first-order kinetics a...

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Bibliographic Details

Published in:	Appl Environ Microbiol
Main Authors:	Johnsen, Line, Fimland, Gunnar, Eijsink, Vincent, Nissen-Meyer, Jon
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2000
Subjects:	Enzymology and Protein Engineering
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC92382/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11055926/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.66.11.4798-4802.2000
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