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Biotransformation of the Antimelanoma Agent Betulinic Acid by Bacillus megaterium ATCC 13368

Microbial transformation of the antimelanoma agent betulinic acid was studied. The main objective of this study was to utilize microorganisms as in vitro models to predict and prepare potential mammalian metabolites of this compound. Preparative-scale biotransformation with resting-cell suspensions...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Principais autores: Chatterjee, Parnali, Kouzi, Samir A., Pezzuto, John M., Hamann, Mark T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC92230/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10966400/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.66.9.3850-3855.2000
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