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Biotransformation of the Antimelanoma Agent Betulinic Acid by Bacillus megaterium ATCC 13368

Microbial transformation of the antimelanoma agent betulinic acid was studied. The main objective of this study was to utilize microorganisms as in vitro models to predict and prepare potential mammalian metabolites of this compound. Preparative-scale biotransformation with resting-cell suspensions...

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Veröffentlicht in:Appl Environ Microbiol
Hauptverfasser: Chatterjee, Parnali, Kouzi, Samir A., Pezzuto, John M., Hamann, Mark T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2000
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC92230/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10966400/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.66.9.3850-3855.2000
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