Mechanism of the Incidental Production of a Melanin-Like Pigment during 6-Demethylchlortetracycline Production in Streptomyces aureofaciens

The secondary metabolite 6-demethylchlortetracycline (6-DCT), which is produced by Streptomyces aureofaciens, is used as a precursor of semisynthetic tetracyclines. Strains that produce 6-DCT also produce a melanin-like pigment (MP). The correlation between MP production and 6-DCT production was inv...

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Publié dans:	Appl Environ Microbiol
Auteurs principaux:	Nakano, Tetsuo, Miyake, Koichiro, Ikeda, Masato, Mizukami, Toru, Katsumata, Ryoichi
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2000
Sujets:	Physiology and Biotechnology
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC91999/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10742218/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.66.4.1400-1404.2000
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