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Mechanism of the Incidental Production of a Melanin-Like Pigment during 6-Demethylchlortetracycline Production in Streptomyces aureofaciens

The secondary metabolite 6-demethylchlortetracycline (6-DCT), which is produced by Streptomyces aureofaciens, is used as a precursor of semisynthetic tetracyclines. Strains that produce 6-DCT also produce a melanin-like pigment (MP). The correlation between MP production and 6-DCT production was inv...

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Detalhes bibliográficos
Main Authors: Nakano, Tetsuo, Miyake, Koichiro, Ikeda, Masato, Mizukami, Toru, Katsumata, Ryoichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC91999/
https://ncbi.nlm.nih.gov/pubmed/10742218
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