Linking Central Metabolism with Increased Pathway Flux: l-Valine Accumulation by Corynebacterium glutamicum

Mutants of Corynebacterium glutamicum were made and enzymatically characterized to clone ilvD and ilvE, which encode dihydroxy acid dehydratase and transaminase B, respectively. These genes of the branched-chain amino acid synthesis were overexpressed together with ilvBN (which encodes acetohydroxy...

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Main Authors: Radmacher, Eva, Vaitsikova, Adela, Burger, Udo, Krumbach, Karin, Sahm, Hermann, Eggeling, Lothar
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
Physiology and Biotechnology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC127577/
https://ncbi.nlm.nih.gov/pubmed/11976094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.68.5.2246-2250.2002
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