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Identification of glyA (Encoding Serine Hydroxymethyltransferase) and Its Use Together with the Exporter ThrE To Increase l-Threonine Accumulation by Corynebacterium glutamicum

l-Threonine can be made by the amino acid-producing bacterium Corynebacterium glutamicum. However, in the course of this process, some of the l-threonine is degraded to glycine. We detected an aldole cleavage activity of l-threonine in crude extracts with an activity of 2.2 nmol min(−1) (mg of prote...

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Autores principales: Simic, Petra, Willuhn, Juliane, Sahm, Hermann, Eggeling, Lothar
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC126772/
https://ncbi.nlm.nih.gov/pubmed/12089010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.68.7.3321-3327.2002
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