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Linking Central Metabolism with Increased Pathway Flux: l-Valine Accumulation by Corynebacterium glutamicum

Mutants of Corynebacterium glutamicum were made and enzymatically characterized to clone ilvD and ilvE, which encode dihydroxy acid dehydratase and transaminase B, respectively. These genes of the branched-chain amino acid synthesis were overexpressed together with ilvBN (which encodes acetohydroxy...

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Autori principali: Radmacher, Eva, Vaitsikova, Adela, Burger, Udo, Krumbach, Karin, Sahm, Hermann, Eggeling, Lothar
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC127577/
https://ncbi.nlm.nih.gov/pubmed/11976094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.68.5.2246-2250.2002
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