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Expression of the Escherichia coli Catabolic Threonine Dehydratase in Corynebacterium glutamicum and Its Effect on Isoleucine Production

The catabolic or biodegradative threonine dehydratase (E.C. 4.2.1.16) of Escherichia coli is an isoleucine feedback-resistant enzyme that catalyzes the degradation of threonine to α-ketobutyrate, the first reaction of the isoleucine pathway. We cloned and expressed this enzyme in Corynebacterium glu...

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Détails bibliographiques
Publié dans:Appl Environ Microbiol
Auteurs principaux: Guillouet, S., Rodal, A. A., An, G.-H., Lessard, P. A., Sinskey, A. J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC91462/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10388709/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.65.7.3100-3107.1999
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