Expression of the Escherichia coli Catabolic Threonine Dehydratase in Corynebacterium glutamicum and Its Effect on Isoleucine Production

The catabolic or biodegradative threonine dehydratase (E.C. 4.2.1.16) of Escherichia coli is an isoleucine feedback-resistant enzyme that catalyzes the degradation of threonine to α-ketobutyrate, the first reaction of the isoleucine pathway. We cloned and expressed this enzyme in Corynebacterium glu...

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Autores principales: Guillouet, S., Rodal, A. A., An, G.-H., Lessard, P. A., Sinskey, A. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1999
Materias:
Physiology and Biotechnology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC91462/
https://ncbi.nlm.nih.gov/pubmed/10388709
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