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Unbalance of L-lysine flux in Corynebacterium glutamicum and its use for the isolation of excretion-defective mutants.

We found that the simple addition of L-methionine to the wild type of Corynebacterium glutamicum results in excretion of the cellular building block L-lysine up to rates of 2.5 nmol/min/mg (dry weight). Biochemical analyses revealed that L-methionine represses the homoserine dehydrogenase activity a...

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Библиографические подробности
Главные авторы: Vrljic, M, Kronemeyer, W, Sahm, H, Eggeling, L
Формат: Artigo
Язык:Inglês
Опубликовано: 1995
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC177132/
https://ncbi.nlm.nih.gov/pubmed/7608075
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