Unbalance of L-lysine flux in Corynebacterium glutamicum and its use for the isolation of excretion-defective mutants.

We found that the simple addition of L-methionine to the wild type of Corynebacterium glutamicum results in excretion of the cellular building block L-lysine up to rates of 2.5 nmol/min/mg (dry weight). Biochemical analyses revealed that L-methionine represses the homoserine dehydrogenase activity a...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	J Bacteriol
Autori principali:	Vrljic, M, Kronemeyer, W, Sahm, H, Eggeling, L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177132/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7608075/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.14.4021-4027.1995
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!