Unbalance of L-lysine flux in Corynebacterium glutamicum and its use for the isolation of excretion-defective mutants.

We found that the simple addition of L-methionine to the wild type of Corynebacterium glutamicum results in excretion of the cellular building block L-lysine up to rates of 2.5 nmol/min/mg (dry weight). Biochemical analyses revealed that L-methionine represses the homoserine dehydrogenase activity a...

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Detalles Bibliográficos

Publicado en:	J Bacteriol
Autores principales:	Vrljic, M, Kronemeyer, W, Sahm, H, Eggeling, L
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1995
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177132/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7608075/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.14.4021-4027.1995
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