Urinary Excretion and Bactericidal Activities of Gemifloxacin and Ofloxacin after a Single Oral Dose in Healthy Volunteers

In a randomized crossover study, 16 volunteers (8 men, 8 women) received single oral doses of 320 mg of gemifloxacin and 400 mg of ofloxacin on two separate occasions in the fasting state to assess the urinary excretion and urinary bactericidal titers (UBTs) at intervals for up to 144 h. Ofloxacin s...

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Main Authors: Naber, Christoph K., Hammer, Michaela, Kinzig-Schippers, Martina, Sauber, Christian, Sörgel, Fritz, Bygate, Elizabeth A., Fairless, Amanda J., Machka, Konstanze, Naber, Kurt G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC90863/
https://ncbi.nlm.nih.gov/pubmed/11709334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.12.3524-3530.2001
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