Effects of Single Oral Doses of Gemifloxacin (320 Milligrams) versus Trovafloxacin (200 Milligrams) on Fecal Flora in Healthy Volunteers

Gemifloxacin and trovafloxacin were administered to 12 volunteers in a randomized crossover trial with a 2-week washout period. Stool samples were collected predose and 1, 2, and 3 days postdose. Both quinolones reduced the number of organisms of the family Enterobacteriaceae and aerobic gram-positi...

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Main Authors: Garcia-Calvo, Gloria, Molleja, Ana, Giménez, Maria J., Parra, Araceli, Nieto, Eva, Ponte, Carmen, Aguilar, Lorenzo, Soriano, Francisco
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Clinical Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC90336/
https://ncbi.nlm.nih.gov/pubmed/11158764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.2.608-611.2001
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