Urinary Excretion and Bactericidal Activities of Gemifloxacin and Ofloxacin after a Single Oral Dose in Healthy Volunteers

In a randomized crossover study, 16 volunteers (8 men, 8 women) received single oral doses of 320 mg of gemifloxacin and 400 mg of ofloxacin on two separate occasions in the fasting state to assess the urinary excretion and urinary bactericidal titers (UBTs) at intervals for up to 144 h. Ofloxacin s...

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Détails bibliographiques
Auteurs principaux: Naber, Christoph K., Hammer, Michaela, Kinzig-Schippers, Martina, Sauber, Christian, Sörgel, Fritz, Bygate, Elizabeth A., Fairless, Amanda J., Machka, Konstanze, Naber, Kurt G.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2001
Sujets:
Pharmacology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC90863/
https://ncbi.nlm.nih.gov/pubmed/11709334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.12.3524-3530.2001
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