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Safety, Tolerance, and Pharmacokinetics of High-Dose Liposomal Amphotericin B (AmBisome) in Patients Infected with Aspergillus Species and Other Filamentous Fungi: Maximum Tolerated Dose Study
We conducted a phase I-II study of the safety, tolerance, and plasma pharmacokinetics of liposomal amphotericin B (L-AMB; AmBisome) in order to determine its maximally tolerated dosage (MTD) in patients with infections due to Aspergillus spp. and other filamentous fungi. Dosage cohorts consisted of...
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Päätekijät: | , , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
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American Society for Microbiology
2001
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Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC90858/ https://ncbi.nlm.nih.gov/pubmed/11709329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.12.3487-3496.2001 |
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