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Safety, Tolerance, and Pharmacokinetics of High-Dose Liposomal Amphotericin B (AmBisome) in Patients Infected with Aspergillus Species and Other Filamentous Fungi: Maximum Tolerated Dose Study

We conducted a phase I-II study of the safety, tolerance, and plasma pharmacokinetics of liposomal amphotericin B (L-AMB; AmBisome) in order to determine its maximally tolerated dosage (MTD) in patients with infections due to Aspergillus spp. and other filamentous fungi. Dosage cohorts consisted of...

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Bibliografiset tiedot
Päätekijät: Walsh, Thomas J., Goodman, Jesse L., Pappas, Peter, Bekersky, Ihor, Buell, Donald N., Roden, Maureen, Barrett, John, Anaissie, Elias J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2001
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC90858/
https://ncbi.nlm.nih.gov/pubmed/11709329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.12.3487-3496.2001
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