In Vitro and In Vivo Effects of Quinupristin-Dalfopristin against Pneumocystis carinii

Quinupristin-dalfopristin (Q-D), which is active against bacteria and Toxoplasma gondii, was examined for its activity against Pneumocystis carinii. After 72 h of incubation with rat P. carinii in an ATP cytotoxicity assay, the 50% inhibitory concentration of Q-D was 10.6 μg/ml, a level that can be...

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Bibliographic Details
Main Authors: Walzer, Peter D., Ashbaugh, Alan, Collins, Margaret, Cushion, Melanie T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC90815/
https://ncbi.nlm.nih.gov/pubmed/11600389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.11.3234-3237.2001
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