Action of Deferoxamine against Pneumocystis carinii

We found earlier that deferoxamine (DFO), a drug used for treatment of iron overload, is active against a rat model of Pneumocystis carinii pneumonia (PCP). We had assumed a mode of action by deprivation of nutritional iron; however, data here show that DFO penetrates P. carinii, causing irreversibl...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Clarkson, Allen B., Turkel-Parrella, David, Williams, Jonathan H., Chen, Lung Chi, Gordon, Terry, Merali, Salim
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2001
Matèries:	Experimental Therapeutics
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90869/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11709340/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.12.3560-3565.2001
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