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In Vitro and In Vivo Effects of Quinupristin-Dalfopristin against Pneumocystis carinii

Quinupristin-dalfopristin (Q-D), which is active against bacteria and Toxoplasma gondii, was examined for its activity against Pneumocystis carinii. After 72 h of incubation with rat P. carinii in an ATP cytotoxicity assay, the 50% inhibitory concentration of Q-D was 10.6 μg/ml, a level that can be...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Walzer, Peter D., Ashbaugh, Alan, Collins, Margaret, Cushion, Melanie T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90815/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11600389/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.11.3234-3237.2001
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