In Vitro and In Vivo Effects of 14α-Demethylase (ERG11) Depletion in Candida glabrata

Sterol 14α-demethylase (ERG11) is the target enzyme of azole antifungals that are widely used for the treatment of fungal infections. Candida glabrata is known to be less susceptible to fluconazole than most Candida albicans strains, and the incidence of C. glabrata infection has been increasing mos...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Autores principales:	Nakayama, Hironobu, Nakayama, Noboru, Arisawa, Mikio, Aoki, Yuko
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Materias:	Mechanisms of Resistance
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90779/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11600353/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.11.3037-3045.2001
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