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In Vitro and In Vivo Effects of 14α-Demethylase (ERG11) Depletion in Candida glabrata

Sterol 14α-demethylase (ERG11) is the target enzyme of azole antifungals that are widely used for the treatment of fungal infections. Candida glabrata is known to be less susceptible to fluconazole than most Candida albicans strains, and the incidence of C. glabrata infection has been increasing mos...

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Bibliografiske detaljer
Main Authors: Nakayama, Hironobu, Nakayama, Noboru, Arisawa, Mikio, Aoki, Yuko
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90779/
https://ncbi.nlm.nih.gov/pubmed/11600353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.11.3037-3045.2001
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