Pharmacokinetic and Pharmacodynamic Modeling of Anidulafungin (LY303366): Reappraisal of Its Efficacy in Neutropenic Animal Models of Opportunistic Mycoses Using Optimal Plasma Sampling

The compartmental pharmacokinetics of anidulafungin (VER-002; formerly LY303366) in plasma were characterized with normal rabbits, and the relationships between drug concentrations and antifungal efficacy were assessed in clinically applicable infection models in persistently neutropenic animals. At...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Groll, Andreas H., Mickiene, Diana, Petraitiene, Ruta, Petraitis, Vidmantas, Lyman, Caron A., Bacher, John S., Piscitelli, Stephen C., Walsh, Thomas J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2001
विषय:
Experimental Therapeutics
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC90741/
https://ncbi.nlm.nih.gov/pubmed/11557479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.10.2845-2855.2001
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