Pharmacokinetic and Pharmacodynamic Modeling of Anidulafungin (LY303366): Reappraisal of Its Efficacy in Neutropenic Animal Models of Opportunistic Mycoses Using Optimal Plasma Sampling

The compartmental pharmacokinetics of anidulafungin (VER-002; formerly LY303366) in plasma were characterized with normal rabbits, and the relationships between drug concentrations and antifungal efficacy were assessed in clinically applicable infection models in persistently neutropenic animals. At...

Szczegółowa specyfikacja

Opis bibliograficzny

Wydane w:	Antimicrob Agents Chemother
Główni autorzy:	Groll, Andreas H., Mickiene, Diana, Petraitiene, Ruta, Petraitis, Vidmantas, Lyman, Caron A., Bacher, John S., Piscitelli, Stephen C., Walsh, Thomas J.
Format:	Artigo
Język:	Inglês
Wydane:	American Society for Microbiology (ASM) 2001
Hasła przedmiotowe:	Experimental Therapeutics
Dostęp online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90741/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11557479/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.10.2845-2855.2001
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