Pharmacokinetic and Pharmacodynamic Modeling of Anidulafungin (LY303366): Reappraisal of Its Efficacy in Neutropenic Animal Models of Opportunistic Mycoses Using Optimal Plasma Sampling

The compartmental pharmacokinetics of anidulafungin (VER-002; formerly LY303366) in plasma were characterized with normal rabbits, and the relationships between drug concentrations and antifungal efficacy were assessed in clinically applicable infection models in persistently neutropenic animals. At...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Groll, Andreas H., Mickiene, Diana, Petraitiene, Ruta, Petraitis, Vidmantas, Lyman, Caron A., Bacher, John S., Piscitelli, Stephen C., Walsh, Thomas J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2001
Aiheet:
Experimental Therapeutics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC90741/
https://ncbi.nlm.nih.gov/pubmed/11557479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.10.2845-2855.2001
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia