β-Lactamase Inhibitors Derived from Single-Domain Antibody Fragments Elicited in the Camelidae

Small, soluble single-domain fragments derived from the unique variable region of dromedary heavy-chain antibodies (VHHs) against enzymes are known to be potent inhibitors. The immunization of dromedaries with the TEM-1 and BcII β-lactamases has lead to the isolation of such single-domain antibody f...

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Dettagli Bibliografici
Autori principali: Conrath, Katja E., Lauwereys, Marc, Galleni, Moreno, Matagne, André, Frère, Jean-Marie, Kinne, Jörg, Wyns, Lode, Muyldermans, Serge
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC90735/
https://ncbi.nlm.nih.gov/pubmed/11557473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.10.2807-2812.2001
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