Cell-Based Fluorescence Assay for Human Immunodeficiency Virus Type 1 Protease Activity

The human immunodeficiency virus type 1 (HIV-1) protease is essential for production of infectious virus and is therefore a major target for the development of drugs against AIDS. Cellular proteins are also cleaved by the protease, which explains its cytotoxic activity and the consequent failure to...

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Bibliografiske detaljer
Main Authors: Lindsten, Kristina, Uhlíková, Tat'ána, Konvalinka, Jan, Masucci, Maria G., Dantuma, Nico P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90701/
https://ncbi.nlm.nih.gov/pubmed/11502538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.9.2616-2622.2001
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