Mutation in the DNA Gyrase A Gene of Escherichia coli That Expands the Quinolone Resistance-Determining Region

In three Escherichia coli mutants, a change (Ala-51 to Val) in the gyrase A protein outside the standard quinolone resistance-determining region (QRDR) lowered the level of quinolone susceptibility more than changes at amino acids 67, 82, 84, and 106 did. Revision of the QRDR to include amino acid 5...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Friedman, S. Marvin, Lu, Tao, Drlica, Karl
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90659/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11451702/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.8.2378-2380.2001
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