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Mutation in the DNA Gyrase A Gene of Escherichia coli That Expands the Quinolone Resistance-Determining Region

In three Escherichia coli mutants, a change (Ala-51 to Val) in the gyrase A protein outside the standard quinolone resistance-determining region (QRDR) lowered the level of quinolone susceptibility more than changes at amino acids 67, 82, 84, and 106 did. Revision of the QRDR to include amino acid 5...

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Bibliografiske detaljer
Main Authors: Friedman, S. Marvin, Lu, Tao, Drlica, Karl
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90659/
https://ncbi.nlm.nih.gov/pubmed/11451702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.8.2378-2380.2001
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