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Mutation in the DNA Gyrase A Gene of Escherichia coli That Expands the Quinolone Resistance-Determining Region

In three Escherichia coli mutants, a change (Ala-51 to Val) in the gyrase A protein outside the standard quinolone resistance-determining region (QRDR) lowered the level of quinolone susceptibility more than changes at amino acids 67, 82, 84, and 106 did. Revision of the QRDR to include amino acid 5...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Friedman, S. Marvin, Lu, Tao, Drlica, Karl
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90659/
https://ncbi.nlm.nih.gov/pubmed/11451702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.8.2378-2380.2001
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