Telithromycin Is Active against Mycobacterium avium in Mice despite Lacking Significant Activity in Standard In Vitro and Macrophage Assays and Is Associated with Low Frequency of Resistance during Treatment

The activity of telithromycin, a new ketolide, was evaluated in vitro and in vivo against Mycobacterium avium complex (MAC) strains. The MIC of telithromycin for several M. avium isolates obtained from the blood of AIDS patients ranged from 16 to >128 μg/ml (MIC at which 90% of isolates are inhibite...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Bermudez, Luiz E., Inderlied, Clark B., Kolonoski, Peter, Wu, Martin, Aralar, Priscilla, Young, Lowell S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Experimental Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90633/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11451676/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.8.2210-2214.2001
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