Telithromycin Is Active against Mycobacterium avium in Mice despite Lacking Significant Activity in Standard In Vitro and Macrophage Assays and Is Associated with Low Frequency of Resistance during Treatment

The activity of telithromycin, a new ketolide, was evaluated in vitro and in vivo against Mycobacterium avium complex (MAC) strains. The MIC of telithromycin for several M. avium isolates obtained from the blood of AIDS patients ranged from 16 to >128 μg/ml (MIC at which 90% of isolates are inhibite...

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Argitaratua izan da:	Antimicrob Agents Chemother
Egile Nagusiak:	Bermudez, Luiz E., Inderlied, Clark B., Kolonoski, Peter, Wu, Martin, Aralar, Priscilla, Young, Lowell S.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 2001
Gaiak:	Experimental Therapeutics
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90633/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11451676/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.8.2210-2214.2001
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