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Antimonial-Mediated DNA Fragmentation in Leishmania infantum Amastigotes

The basic treatment of leishmaniasis consists in the administration of pentavalent antimonials. The mechanisms that contribute to pentavalent antimonial toxicity against the intracellular stage of the parasite (i.e., amastigote) are still unknown. In this study, the combined use of several technique...

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Autori principali: Sereno, Denis, Holzmuller, Philippe, Mangot, Isabelle, Cuny, Gérard, Ouaissi, Ali, Lemesre, Jean-Loup
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC90601/
https://ncbi.nlm.nih.gov/pubmed/11408224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.7.2064-2069.2001
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