Antimonial-Mediated DNA Fragmentation in Leishmania infantum Amastigotes

The basic treatment of leishmaniasis consists in the administration of pentavalent antimonials. The mechanisms that contribute to pentavalent antimonial toxicity against the intracellular stage of the parasite (i.e., amastigote) are still unknown. In this study, the combined use of several technique...

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Autors principals: Sereno, Denis, Holzmuller, Philippe, Mangot, Isabelle, Cuny, Gérard, Ouaissi, Ali, Lemesre, Jean-Loup
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Mechanisms of Action: Physiological Effects
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC90601/
https://ncbi.nlm.nih.gov/pubmed/11408224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.7.2064-2069.2001
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