Inhibition of Fumarate Reductase in Leishmania major and L. donovani by Chalcones

Our previous studies have shown that chalcones exhibit potent antileishmanial and antimalarial activities in vitro and in vivo. Preliminary studies showed that these compounds destroyed the ultrastructure of Leishmania parasite mitochondria and inhibited the respiration and the activity of mitochond...

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Bibliografiske detaljer
Main Authors: Chen, Ming, Zhai, Lin, Christensen, Søren Brøgger, Theander, Thor G., Kharazmi, Arsalan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90595/
https://ncbi.nlm.nih.gov/pubmed/11408218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.7.2023-2029.2001
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