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Inhibition of Fumarate Reductase in Leishmania major and L. donovani by Chalcones
Our previous studies have shown that chalcones exhibit potent antileishmanial and antimalarial activities in vitro and in vivo. Preliminary studies showed that these compounds destroyed the ultrastructure of Leishmania parasite mitochondria and inhibited the respiration and the activity of mitochond...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC90595/ https://ncbi.nlm.nih.gov/pubmed/11408218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.7.2023-2029.2001 |
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