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Inhibition of Fumarate Reductase in Leishmania major and L. donovani by Chalcones

Our previous studies have shown that chalcones exhibit potent antileishmanial and antimalarial activities in vitro and in vivo. Preliminary studies showed that these compounds destroyed the ultrastructure of Leishmania parasite mitochondria and inhibited the respiration and the activity of mitochond...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Ming, Zhai, Lin, Christensen, Søren Brøgger, Theander, Thor G., Kharazmi, Arsalan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90595/
https://ncbi.nlm.nih.gov/pubmed/11408218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.7.2023-2029.2001
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