Inhibition of Fumarate Reductase in Leishmania major and L. donovani by Chalcones

Our previous studies have shown that chalcones exhibit potent antileishmanial and antimalarial activities in vitro and in vivo. Preliminary studies showed that these compounds destroyed the ultrastructure of Leishmania parasite mitochondria and inhibited the respiration and the activity of mitochond...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Chen, Ming, Zhai, Lin, Christensen, Søren Brøgger, Theander, Thor G., Kharazmi, Arsalan
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Assuntos:	Mechanisms of Action: Physiological Effects
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90595/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11408218/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.7.2023-2029.2001
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