Interaction between DNA Gyrase and Quinolones: Effects of Alanine Mutations at GyrA Subunit Residues Ser(83) and Asp(87)
DNA gyrase is a target of quinolone antibacterial agents, but the molecular details of the quinolone-gyrase interaction are not clear. Quinolone resistance mutations frequently occur at residues Ser(83) and Asp(87) of the gyrase A subunit, suggesting that these residues are involved in drug binding....
Kaydedildi:
| Yayımlandı: | Antimicrob Agents Chemother |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
2001
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90591/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11408214/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.7.1994-2000.2001 |
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