Real-Time PCR and Melting Curve Analysis for Reliable and Rapid Detection of SHV Extended-Spectrum β-Lactamases

Extended-spectrum β-lactamases (ESBLs), e.g., ESBLs of the TEM or SHV type, compromise the efficacies of expanded-spectrum cephalosporins. An SHV non-ESBL that hydrolyzes only narrow-spectrum cephalosporins can be converted into an SHV ESBL through substitutions at three amino acid positions, 179, 2...

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Bibliografiske detaljer
Main Authors: Randegger, Corinne C., Hächler, Herbert
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90538/
https://ncbi.nlm.nih.gov/pubmed/11353618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.6.1730-1736.2001
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