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Contribution of Natural Amino Acid Substitutions in SHV Extended-Spectrum β-Lactamases to Resistance against Various β-Lactams

SHV extended-spectrum β-lactamases (ESBLs) arise through single amino acid substitutions in the parental enzyme, SHV-1. In order to evaluate the effect of genetic dissimilarities around the structural gene on MICs, we had previously devised an isogenic system of strains. Here, we present an extended...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Randegger, Corinne C., Keller, André, Irla, Michel, Wada, Akihito, Hächler, Herbert
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2000
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC90148/
https://ncbi.nlm.nih.gov/pubmed/10991857
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