Prevention and Treatment of Lethal Murine Endotoxemia by the Novel Immunomodulatory Agent MFP-14

Multifunctional protein 14 (MFP-14) is a ubiquitous protein that inhibits the production of tumor necrosis factor alpha (TNF-α) and gamma interferon (IFN-γ), which are involved in the pathogenesis of sepsis. Here, lipopolysaccharide (LPS)-induced lethality in mice was markedly reduced by MFP-14. The...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Nicoletti, Ferdinando, Di Marco, Roberto, Sacerdote, Paola, Meroni, PierLuigi, Mangano, Katia, Edwards, Carl, Bartorelli, Alberto, Bendtzen, Klaus, Panerai, Alberto
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2001
Sujets:	Biologic Response Modifiers
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90515/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11302837/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.5.1591-1594.2001
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