Prevention and Treatment of Lethal Murine Endotoxemia by the Novel Immunomodulatory Agent MFP-14

Multifunctional protein 14 (MFP-14) is a ubiquitous protein that inhibits the production of tumor necrosis factor alpha (TNF-α) and gamma interferon (IFN-γ), which are involved in the pathogenesis of sepsis. Here, lipopolysaccharide (LPS)-induced lethality in mice was markedly reduced by MFP-14. The...

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Detalhes bibliográficos
Main Authors: Nicoletti, Ferdinando, Di Marco, Roberto, Sacerdote, Paola, Meroni, PierLuigi, Mangano, Katia, Edwards, Carl, Bartorelli, Alberto, Bendtzen, Klaus, Panerai, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2001
Assuntos:
Biologic Response Modifiers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90515/
https://ncbi.nlm.nih.gov/pubmed/11302837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.5.1591-1594.2001
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