Improved Efficacy of Ciprofloxacin Administered in Polyethylene Glycol-Coated Liposomes for Treatment of Klebsiella pneumoniae Pneumonia in Rats

Animal and clinical data show that high ratios of the area under the concentration-time curve and the peak concentration in blood to the MIC of fluoroquinolones for a given pathogen are associated with a favorable outcome. The present study investigated whether improvement of the therapeutic potenti...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Bakker-Woudenberg, Irma A. J. M., ten Kate, Marian T., Guo, Luke, Working, Peter, Mouton, Johan W.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Materias:	Experimental Therapeutics
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90493/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11302815/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.5.1487-1492.2001
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