Therapeutic Efficacy of Liposome-Encapsulated Gentamicin in Rat Klebsiella pneumoniae Pneumonia in Relation to Impaired Host Defense and Low Bacterial Susceptibility to Gentamicin

Long-circulating liposomes (LCL) may be used as targeted antimicrobial drug carriers as they localize at sites of infection. As a result, LCL-encapsulated gentamicin (LE-GEN) has demonstrated superior antibacterial activity over the free drug in a single-dose study of immunocompetent rats with Klebs...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Schiffelers, Raymond M., Storm, Gert, ten Kate, Marian T., Bakker-Woudenberg, Irma A. J. M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Experimental Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90314/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158742/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.2.464-470.2001
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!